Harvoni is used to treat people with HCV genotypes 1, 4, 5, and 6. Harvoni is a combination pill made up of the drugs ledipasvir and sofosbuvir.Īs DAAs, these drugs work by interfering with the action of a protein needed for the growth of HCV. Harvoni was the first combination pill that allowed people with genotype 1 to follow an all-oral medication regimen. DAAs are a major step forward in the ongoing effort to treat HCV.

These new drugs, called direct-acting antivirals (DAAs), can directly attack HCV and prevent the virus from replicating. Genotype 1 is the most common in the United States.

HCV strains include genotypes 1, 2, 3, 4, 5, and 6. Many people using this medication do not have serious side effects. A genotype is the particular strain of a virus. If any of these effects last or get worse, tell your doctor or pharmacist promptly.Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Let your healthcare provider know immediately if your side effects do not go away or become bothersome. Researchers began to develop drugs that could effectively target the particular genotype of HCV. Sovaldi may cause little to no side effects in some people. In the early 2000s, researchers began to develop more effective ways to cure HCV. FATIGUE, INSOMNIA, Now for me I felt Overwhelmed at times. FATIGUE, INSOMNIA, Now for me I felt Overwhelmed at times. SIDE EFFECTS: See also Warning section.Tiredness, headache, nausea, diarrhea, itchy skin, difficulty sleeping, or irritability may occur. These medications often came with serious side effects, and they weren’t always effective. Its a great medication, but the side effects are sometimes horrible. For many years, there were only a few medications available to treat HCV, such as interferons and ribavirin.

Sovaldi side effect